Glyco-Flex II contains Perna canaliculus, Glucosamine HCl, Dimethylglycine, Methylsulfonylmethane, and manganese for added joint support. Methylsulfonylmethane also provides added comfort during recovery.It is part of the Vetri-Science® stage of life program. STAGE 2, REBUILD, for moderate stages of joint dysfunction. Glyco-Flex® II offers a comprehensive support for joints and connective tissue health that helps with recovery from sprains, joint injuries, and as a follow-up to orthopedic surgeries.Directions for use: Initial: (4-6 Weeks) Up to 30lbs: 1/2 tablet daily 31lb-60lbs: 1 tablet daily 61-100lbs: 2 tablet daily 101lbs and over: 2 1/2 tablet dailyMaintenance: (After initial period) Up to 30lbs: 1/2 tablet daily 31lb-60lbs: 1/2 tablet daily 61-100lbs: 1 tablet daily 101lbs and over: 1 1/2 tablet dailyIf giving more than 1 tablet, divide between AM and PM.