Novifit L 3 PACK (90 Tablets) 400mg: Helps support Cognitive function of aging dogs Active Ingredient (per tablet): SAMe/S-Adenosyl-L-Methionine-Tosylate Disulfate …… 400mg Direction: For Dogs between 44 and 88 lbs: 1 tablet once a day for a period of 1 to 2 months. For Dogs over 88 lbs: 1 tablet twice a day for a period of 1 to 2 months.